Vitamin D and Bone BoneHealthGordon

Osteoporosis

  • Preventable disease
  • No cure
  • New interest in childhood and adolescence as critical years for bone acquisition

 Gender and Race

Males:

  • Higher bone mass at all ages
  • Higher peak bone mass
  • Slower decline of sex steroids

Osteoporosis/Fractures:

  • lower among African Americans (higher peak bone mass in both males and females)

 Genetic Factors

  • Striking patterns within families
  • §Premenopausal daughters of postmenopausal women with osteoporosis: lower BMD
  • Candidate genes

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